Adenovirus-associated anti-miRNA-214 regulates bone metabolism and prevents local osteoporosis in rats

Objective: We investigated the expression of miRNA-214 in human osteoporotic bone tissue and tested the utility of adeno-associated virus (AAV) expressing a miRNA-214 inhibitor in terms of preventing local osteoporosis of the femoral condyle in a rat model of osteoporosis. Methods: (1) Femoral heads...

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Detalles Bibliográficos
Autores principales: Wang, Cheng, Wang, Peng, Li, Feng, Li, Yang, Zhao, Minwei, Feng, Hui, Meng, Haoye, Li, Junyang, Shi, Peng, Peng, Jiang, Tian, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214158/
https://www.ncbi.nlm.nih.gov/pubmed/37251576
http://dx.doi.org/10.3389/fbioe.2023.1164252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214158/
https://www.ncbi.nlm.nih.gov/pubmed/37251576
http://dx.doi.org/10.3389/fbioe.2023.1164252

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