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Cargo-selective and adaptive delivery of nucleic acid therapeutics by bola-amphiphilic dendrimers

Nucleic acid therapeutics are becoming an important drug modality, offering the unique opportunity to address “undruggable” targets, respond rapidly to evolving pathogens, and treat diseases at the gene level for precision medicine. However, nucleic acid therapeutics have poor bioavailability and ar...

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Detalles Bibliográficos
Autores principales: Chen, Jiaxuan, Zhu, Dandan, Lian, Baoping, Shi, Kangjie, Chen, Peng, Li, Ying, Lin, Wenyi, Ding, Ling, Long, Qiulin, Wang, Yang, Laurini, Erik, Lan, Wenjun, Li, Yun, Tintaru, Aura, Ju, Caoyun, Zhang, Can, Pricl, Sabrina, Iovanna, Juan, Liu, Xiaoxuan, Peng, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214173/
https://www.ncbi.nlm.nih.gov/pubmed/37186846
http://dx.doi.org/10.1073/pnas.2220787120