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Cargo-selective and adaptive delivery of nucleic acid therapeutics by bola-amphiphilic dendrimers
Nucleic acid therapeutics are becoming an important drug modality, offering the unique opportunity to address “undruggable” targets, respond rapidly to evolving pathogens, and treat diseases at the gene level for precision medicine. However, nucleic acid therapeutics have poor bioavailability and ar...
Autores principales: | Chen, Jiaxuan, Zhu, Dandan, Lian, Baoping, Shi, Kangjie, Chen, Peng, Li, Ying, Lin, Wenyi, Ding, Ling, Long, Qiulin, Wang, Yang, Laurini, Erik, Lan, Wenjun, Li, Yun, Tintaru, Aura, Ju, Caoyun, Zhang, Can, Pricl, Sabrina, Iovanna, Juan, Liu, Xiaoxuan, Peng, Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214173/ https://www.ncbi.nlm.nih.gov/pubmed/37186846 http://dx.doi.org/10.1073/pnas.2220787120 |
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