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Deciphering molecular mechanisms stabilizing the reovirus-binding complex

Mammalian orthoreoviruses (reoviruses) serve as potential triggers of celiac disease and have oncolytic properties, making these viruses potential cancer therapeutics. Primary attachment of reovirus to host cells is mainly mediated by the trimeric viral protein, σ1, which engages cell-surface glycan...

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Detalles Bibliográficos
Autores principales: dos Santos Natividade, Rita, Koehler, Melanie, Gomes, Priscila S. F. C., Simpson, Joshua D., Smith, Sydni Caet, Gomes, Diego E. B., de Lhoneux, Juliette, Yang, Jinsung, Ray, Ankita, Dermody, Terence S., Bernardi, Rafael C., Ogden, Kristen M., Alsteens, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214207/
https://www.ncbi.nlm.nih.gov/pubmed/37186838
http://dx.doi.org/10.1073/pnas.2220741120