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A genome-wide CRISPR screen maps endogenous regulators of PPARG gene expression in bladder cancer
Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor central in the regulation of key cellular processes including cell metabolism, tissue differentiation, and regulation of the immune system. PPARγ is required for normal differentiation of the urothelium and is thought to...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214290/ https://www.ncbi.nlm.nih.gov/pubmed/37250326 http://dx.doi.org/10.1016/j.isci.2023.106525 |