A genome-wide CRISPR screen maps endogenous regulators of PPARG gene expression in bladder cancer

Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor central in the regulation of key cellular processes including cell metabolism, tissue differentiation, and regulation of the immune system. PPARγ is required for normal differentiation of the urothelium and is thought to...

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Detalles Bibliográficos
Autores principales: Tortora, Davide, Roberts, Morgan E., Kumar, Gunjan, Kotapalli, Sudha S., Ritch, Elie, Scurll, Joshua M., McConeghy, Brian, Sinha, Sunita, Wyatt, Alexander W., Black, Peter C., Daugaard, Mads
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214290/
https://www.ncbi.nlm.nih.gov/pubmed/37250326
http://dx.doi.org/10.1016/j.isci.2023.106525

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