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Gintonin, a Panax ginseng-derived LPA receptor ligand, attenuates kainic acid-induced seizures and neuronal cell death in the hippocampus via anti-inflammatory and anti-oxidant activities

BACKGROUND: Gintonin (GT), a Panax ginseng-derived lysophosphatidic acid receptor (LPAR) ligand, has positive effects in cultured or animal models for Parkinson's disease, Huntington's disease, and so on. However, the potential therapeutic value of GT in treating epilepsy has not yet been...

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Detalles Bibliográficos
Autores principales: Choi, Jong Hee, Kwon, Tae Woo, Jo, Hyo Sung, Ha, Yujeong, Cho, Ik-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214296/
https://www.ncbi.nlm.nih.gov/pubmed/37252272
http://dx.doi.org/10.1016/j.jgr.2022.11.001