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Gintonin, a Panax ginseng-derived LPA receptor ligand, attenuates kainic acid-induced seizures and neuronal cell death in the hippocampus via anti-inflammatory and anti-oxidant activities
BACKGROUND: Gintonin (GT), a Panax ginseng-derived lysophosphatidic acid receptor (LPAR) ligand, has positive effects in cultured or animal models for Parkinson's disease, Huntington's disease, and so on. However, the potential therapeutic value of GT in treating epilepsy has not yet been...
Autores principales: | Choi, Jong Hee, Kwon, Tae Woo, Jo, Hyo Sung, Ha, Yujeong, Cho, Ik-Hyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214296/ https://www.ncbi.nlm.nih.gov/pubmed/37252272 http://dx.doi.org/10.1016/j.jgr.2022.11.001 |
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