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Phase I randomized, observer-blinded, placebo-controlled study of a SARS-CoV-2 mRNA vaccine PTX-COVID19-B

Access to vaccines against SARS-CoV-2 virus was limited in poor countries during the COVID-19 pandemic. Therefore, a low-cost mRNA vaccine, PTX-COVID19-B, was produced and evaluated in a Phase 1 trial. PTX-COVID19-B encodes Spike protein D614G variant without the proline-proline (986–987) mutation p...

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Detalles Bibliográficos
Autores principales: Martin-Orozco, Natalia, Vale, Noah, Mihic, Alan, Amor, Talya, Reiter, Lawrence, Arita, Yuko, Samson, Reuben, Hu, Queenie, Gingras, Anne-Claude, Sorenson, Bradley Thomas, Marcusson, Eric Gates, Patel, Piyush
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214351/
https://www.ncbi.nlm.nih.gov/pubmed/37236995
http://dx.doi.org/10.1038/s41598-023-35662-y