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SOX18-enforced expression diverts hemogenic endothelium-derived progenitors from T towards NK lymphoid pathways

Hemogenic endothelium (HE) is the main source of blood cells in the embryo. To improve blood manufacturing from human pluripotent stem cells (hPSCs), it is essential to define the molecular determinants that enhance HE specification and promote development of the desired blood lineage from HE. Here,...

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Detalles Bibliográficos
Autores principales: Jung, Ho Sun, Suknuntha, Kran, Kim, Yun Hee, Liu, Peng, Dettle, Samuel T., Sedzro, Divine Mensah, Smith, Portia R., Thomson, James A., Ong, Irene M., Slukvin, Igor I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214392/
https://www.ncbi.nlm.nih.gov/pubmed/37250328
http://dx.doi.org/10.1016/j.isci.2023.106621