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Large-scale microRNA functional high-throughput screening identifies miR-515-3p and miR-519e-3p as inducers of human cardiomyocyte proliferation

Ischemic cardiomyopathy, driven by loss of cardiomyocytes and inadequate proliferative response, persists to be a major global health problem. Using a functional high-throughput screening, we assessed differential proliferative potential of 2019 miRNAs after transient hypoxia by transfecting both mi...

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Detalles Bibliográficos
Autores principales: Renikunta, Harsha V., Lazarow, Katina, Gong, Yiqi, Shukla, Praphulla Chandra, Nageswaran, Vanasa, Giral, Hector, Kratzer, Adelheid, Opitz, Lennart, Engel, Felix B., Haghikia, Arash, Costantino, Sarah, Paneni, Francesco, von Kries, Jens Peter, Streckfuss-Bömeke, Katrin, Landmesser, Ulf, Jakob, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214393/
https://www.ncbi.nlm.nih.gov/pubmed/37250320
http://dx.doi.org/10.1016/j.isci.2023.106593