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Neutralization of Intracellular pH Homeostasis to Inhibit Osteoclasts Based on a Spatiotemporally Selective Delivery System
[Image: see text] Osteoporosis is a global disease caused by abnormal overactivation of osteoclasts. The acidic environment in sealing zone of osteoclasts with H(+) pumped from cytoplasm is critical to the maturation of osteoclasts. Therefore, reducing the intracellular H(+) concentration can reduce...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214447/ https://www.ncbi.nlm.nih.gov/pubmed/37183806 http://dx.doi.org/10.1021/acs.nanolett.2c04295 |