eIF4E phosphorylation recruits β-catenin to mRNA cap and promotes Wnt pathway translation in dentate gyrus LTP maintenance

The mRNA cap-binding protein, eukaryotic initiation factor 4E (eIF4E), is crucial for translation and regulated by Ser209 phosphorylation. However, the biochemical and physiological role of eIF4E phosphorylation in translational control of long-term synaptic plasticity is unknown. We demonstrate tha...

Descripción completa

Detalles Bibliográficos
Autores principales: Patil, Sudarshan, Chalkiadaki, Kleanthi, Mergiya, Tadiwos F., Krimbacher, Konstanze, Amorim, Inês S., Akerkar, Shreeram, Gkogkas, Christos G., Bramham, Clive R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214474/
https://www.ncbi.nlm.nih.gov/pubmed/37250335
http://dx.doi.org/10.1016/j.isci.2023.106649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214474/
https://www.ncbi.nlm.nih.gov/pubmed/37250335
http://dx.doi.org/10.1016/j.isci.2023.106649

Ejemplares similares