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eIF4E phosphorylation recruits β-catenin to mRNA cap and promotes Wnt pathway translation in dentate gyrus LTP maintenance
The mRNA cap-binding protein, eukaryotic initiation factor 4E (eIF4E), is crucial for translation and regulated by Ser209 phosphorylation. However, the biochemical and physiological role of eIF4E phosphorylation in translational control of long-term synaptic plasticity is unknown. We demonstrate tha...
Autores principales: | Patil, Sudarshan, Chalkiadaki, Kleanthi, Mergiya, Tadiwos F., Krimbacher, Konstanze, Amorim, Inês S., Akerkar, Shreeram, Gkogkas, Christos G., Bramham, Clive R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214474/ https://www.ncbi.nlm.nih.gov/pubmed/37250335 http://dx.doi.org/10.1016/j.isci.2023.106649 |
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