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Straightforward synthesis of N-arylindoles via one-pot Fischer indolisation–indole N-arylation

A microwave-promoted, one-pot, three-component synthesis of N-arylindoles has been developed, utilising sequential Fischer indolisation then copper(i)-catalysed indole N-arylation. Novel arylation conditions were identified that use a simple and cheap catalyst/base system (Cu(2)O/K(3)PO(4)) in an en...

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Detalles Bibliográficos
Autores principales: Lintott, Mia, Perry, Alexis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214496/
https://www.ncbi.nlm.nih.gov/pubmed/37250219
http://dx.doi.org/10.1039/d3ra02658b