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A Turn-On Fluorescent Amino Acid Sensor Reveals Chloroquine’s Effect on Cellular Amino Acids via Inhibiting Cathepsin L

[Image: see text] Maintaining homeostasis of metabolites such as amino acids is critical for cell survival. Dysfunction of nutrient balance can result in human diseases such as diabetes. Much remains to be discovered about how cells transport, store, and utilize amino acids due to limited research t...

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Detalles Bibliográficos
Autores principales: Smith, Michael R., Zhang, Le, Jin, Yizhen, Yang, Min, Bade, Anusha, Gillis, Kevin D., Jana, Sadhan, Bypaneni, Ramesh Naidu, Glass, Timothy E., Lin, Hening
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214525/
https://www.ncbi.nlm.nih.gov/pubmed/37252359
http://dx.doi.org/10.1021/acscentsci.2c01325