Conformational Dynamics of the Activated GLP-1 Receptor-G(s) Complex Revealed by Cross-Linking Mass Spectrometry and Integrative Structure Modeling

[Image: see text] Despite advances in characterizing the structures and functions of G protein-coupled receptors (GPCRs), our understanding of GPCR activation and signaling is still limited by the lack of information on conformational dynamics. It is particularly challenging to study the dynamics of...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Shijia, Xia, Lisha, Wang, Chenxi, Wu, Fan, Zhang, Bingjie, Pan, Chen, Fan, Zhiran, Lei, Xiaoguang, Stevens, Raymond C., Sali, Andrej, Sun, Liping, Shui, Wenqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214531/
https://www.ncbi.nlm.nih.gov/pubmed/37252352
http://dx.doi.org/10.1021/acscentsci.3c00063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214531/
https://www.ncbi.nlm.nih.gov/pubmed/37252352
http://dx.doi.org/10.1021/acscentsci.3c00063

Ejemplares similares