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Conformational Dynamics of the Activated GLP-1 Receptor-G(s) Complex Revealed by Cross-Linking Mass Spectrometry and Integrative Structure Modeling

[Image: see text] Despite advances in characterizing the structures and functions of G protein-coupled receptors (GPCRs), our understanding of GPCR activation and signaling is still limited by the lack of information on conformational dynamics. It is particularly challenging to study the dynamics of...

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Detalles Bibliográficos
Autores principales:	Yuan, Shijia, Xia, Lisha, Wang, Chenxi, Wu, Fan, Zhang, Bingjie, Pan, Chen, Fan, Zhiran, Lei, Xiaoguang, Stevens, Raymond C., Sali, Andrej, Sun, Liping, Shui, Wenqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214531/ https://www.ncbi.nlm.nih.gov/pubmed/37252352 http://dx.doi.org/10.1021/acscentsci.3c00063

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