Enzymatic Fluoromethylation Enabled by the S-Adenosylmethionine Analog Te-Adenosyl-L-(fluoromethyl)homotellurocysteine

[Image: see text] Fluoromethyl, difluoromethyl, and trifluoromethyl groups are present in numerous pharmaceuticals and agrochemicals, where they play critical roles in the efficacy and metabolic stability of these molecules. Strategies for late-stage incorporation of fluorine-containing atoms in mol...

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Detalles Bibliográficos
Autores principales: Neti, Syam Sundar, Wang, Bo, Iwig, David F., Onderko, Elizabeth L., Booker, Squire J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214534/
https://www.ncbi.nlm.nih.gov/pubmed/37252363
http://dx.doi.org/10.1021/acscentsci.2c01385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214534/
https://www.ncbi.nlm.nih.gov/pubmed/37252363
http://dx.doi.org/10.1021/acscentsci.2c01385

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