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PCSK9 promotes T helper 1 and T helper 17 cell differentiation by activating the nuclear factor‐κB pathway in ankylosing spondylitis

OBJECTIVE: Our previous study reveals that proprotein convertase subtilisin/kexin type 9 (PCSK9) is positively related to inflammatory markers, T helper (Th)‐17 cells, and treatment response in ankylosing spondylitis (AS) patients. Subsequently, this study aimed to explore the effect of PCSK9 on Th...

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Detalles Bibliográficos
Autores principales: Cai, Jianfei, Jiang, Yinghui, Chen, Fucai, Wu, Shubin, Ren, Hongjun, Wang, Pingping, Wang, Jiayong, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214583/
https://www.ncbi.nlm.nih.gov/pubmed/37249282
http://dx.doi.org/10.1002/iid3.870