Metformin promotes female germline stem cell proliferation by upregulating Gata-binding protein 2 with histone β-hydroxybutyrylation

BACKGROUND: Metformin as a first-line clinical anti-diabetic agent prolongs the lifespan of model animals and promotes cell proliferation. However, the molecular mechanisms underlying the proliferative phenotype, especially in epigenetics, have rarely been reported. The aim of this study was to inve...

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Detalles Bibliográficos
Autores principales: Wang, Xiang, Tian, Geng G., Cheng, Weiwei, Yu, Xiaoli, Li, Xiaoyong, Wu, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214601/
https://www.ncbi.nlm.nih.gov/pubmed/37231495
http://dx.doi.org/10.1186/s13287-023-03360-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214601/
https://www.ncbi.nlm.nih.gov/pubmed/37231495
http://dx.doi.org/10.1186/s13287-023-03360-1

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