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Galectins use N-glycans of FGFs to capture growth factors at the cell surface and fine-tune their signaling

Fibroblast growth factors (FGFs) and their receptors (FGFRs) constitute complex signaling hubs that are crucial for the development and homeostasis of the human body. Most of FGFs are released by cells using the conventional secretory pathway and are N-glycosylated, yet the role of FGFs glycosylatio...

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Detalles Bibliográficos
Autores principales: Gedaj, Aleksandra, Zukowska, Dominika, Porebska, Natalia, Pozniak, Marta, Krzyscik, Mateusz, Czyrek, Aleksandra, Krowarsch, Daniel, Zakrzewska, Malgorzata, Otlewski, Jacek, Opalinski, Lukasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214663/
https://www.ncbi.nlm.nih.gov/pubmed/37231412
http://dx.doi.org/10.1186/s12964-023-01144-x