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Liposomes targeting the cancer cell-exposed receptor, claudin-4, for pancreatic cancer chemotherapy

BACKGROUND: Claudin-4 (CLDN4), a tight junction protein, is overexpressed in several types of cancer, and is considered a biomarker for cancer-targeted treatment. CLDN4 is not exposed in normal cells, but becomes accessible in cancer cells, in which tight junctions are weakened. Notably, surface-exp...

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Detalles Bibliográficos
Autores principales: Bang, Chaeeun, Park, Min Gyu, Cho, In Kyung, Lee, Da-Eun, Kim, Gye Lim, Jang, Eun Hyang, Shim, Man Kyu, Yoon, Hong Yeol, Lee, Sangmin, Kim, Jong-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214683/
https://www.ncbi.nlm.nih.gov/pubmed/37237291
http://dx.doi.org/10.1186/s40824-023-00394-7