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Liposomes targeting the cancer cell-exposed receptor, claudin-4, for pancreatic cancer chemotherapy
BACKGROUND: Claudin-4 (CLDN4), a tight junction protein, is overexpressed in several types of cancer, and is considered a biomarker for cancer-targeted treatment. CLDN4 is not exposed in normal cells, but becomes accessible in cancer cells, in which tight junctions are weakened. Notably, surface-exp...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214683/ https://www.ncbi.nlm.nih.gov/pubmed/37237291 http://dx.doi.org/10.1186/s40824-023-00394-7 |