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Dopamine D2 receptor on CD4(+) T cells is protective against inflammatory responses and signs in a mouse model of rheumatoid arthritis

BACKGROUND: Dopamine is a neurotransmitter and has been found to regulate lymphocytes by acting on dopamine receptors (DRs). CD4(+) T cells express all the five subtypes of DRs, D1R to D5R. Although CD4(+) T cells have been involved in pathogenesis of rheumatoid arthritis (RA), roles of DRs expresse...

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Detalles Bibliográficos
Autores principales: Wang, Xiao-Qin, Cai, Huan-Huan, Deng, Qiao-Wen, Chang, Ya-Zhou, Peng, Yu-Ping, Qiu, Yi-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214709/
https://www.ncbi.nlm.nih.gov/pubmed/37237413
http://dx.doi.org/10.1186/s13075-023-03071-1