Deubiquitinase USP1 influences the dedifferentiation of mouse pancreatic β-cells

Loss of insulin-secreting β-cells in diabetes may be either due to apoptosis or dedifferentiation of β-cell mass. The ubiquitin-proteasome system comprising E3 ligase and deubiquitinases (DUBs) controls several aspects of β-cell functions. In this study, screening for key DUBs identified USP1 to be...

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Detalles Bibliográficos
Autores principales: Francis, Meenal, Bhaskar, Smitha, Komanduri, Saarwani, Sheshadri, Preethi, Prasanna, Jyothi, Kumar, Anujith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214732/
https://www.ncbi.nlm.nih.gov/pubmed/37250303
http://dx.doi.org/10.1016/j.isci.2023.106771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214732/
https://www.ncbi.nlm.nih.gov/pubmed/37250303
http://dx.doi.org/10.1016/j.isci.2023.106771

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