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Copy number variations and protein expression of Cyclin E1 and Epithelial cell transforming sequence 2 genes predict the chemotherapeutic response in patients with serous ovarian carcinoma

BACKGROUND & OBJECTIVES: Serous ovarian carcinoma (SOC) is characterized by extreme genomic instability, chromosomal rearrangements and copy number variations (CNVs) leading to the development of early metastasis and chemo-resistance. The present study was designed to observe the role of CNVs of...

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Detalles Bibliográficos
Autores principales: Sarfraz, Rahat, Masood, Atika, Zaki, Saima, Shami, Amira, Khaliq, Saba, Naseem, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Professional Medical Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214807/
https://www.ncbi.nlm.nih.gov/pubmed/37250533
http://dx.doi.org/10.12669/pjms.39.3.7304