Engineering of inhalable nano-in-microparticles for co-delivery of small molecules and miRNAs

In this study, novel Trojan particles were engineered for direct delivery of doxorubicin (DOX) and miR-34a as model drugs to the lungs to raise local drug concentration, decrease pulmonary clearance, increase lung drug deposition, reduce systemic side effects, and overcome multi-drug resistance. For...

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Detalles Bibliográficos
Autores principales: Motiei, Marjan, Mišík, Ondrej, Truong, Thanh Huong, Lizal, Frantisek, Humpolíček, Petr, Sedlařík, Vladimír, Sáha, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214903/
https://www.ncbi.nlm.nih.gov/pubmed/37382704
http://dx.doi.org/10.1186/s11671-023-03781-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214903/
https://www.ncbi.nlm.nih.gov/pubmed/37382704
http://dx.doi.org/10.1186/s11671-023-03781-0

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