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Engineering of inhalable nano-in-microparticles for co-delivery of small molecules and miRNAs
In this study, novel Trojan particles were engineered for direct delivery of doxorubicin (DOX) and miR-34a as model drugs to the lungs to raise local drug concentration, decrease pulmonary clearance, increase lung drug deposition, reduce systemic side effects, and overcome multi-drug resistance. For...
Autores principales: | Motiei, Marjan, Mišík, Ondrej, Truong, Thanh Huong, Lizal, Frantisek, Humpolíček, Petr, Sedlařík, Vladimír, Sáha, Petr |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214903/ https://www.ncbi.nlm.nih.gov/pubmed/37382704 http://dx.doi.org/10.1186/s11671-023-03781-0 |
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