APTX acts in DNA double-strand break repair in a manner distinct from XRCC4

Aprataxin (APTX), the product of the causative gene for hereditary neurogenerative syndromes Ataxia-oculomotor apraxia 1 and early onset ataxia with oculomotor apraxia and hypoalbuminemia, has an enzymatic activity of removing adenosine monophosphate from DNA 5′-end, which arises from abortive ligat...

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Detalles Bibliográficos
Autores principales: Imamura, Rikiya, Saito, Mizuki, Shimada, Mikio, Kobayashi, Junya, Ishiai, Masamichi, Matsumoto, Yoshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Regular paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214999/
https://www.ncbi.nlm.nih.gov/pubmed/36940705
http://dx.doi.org/10.1093/jrr/rrad007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214999/
https://www.ncbi.nlm.nih.gov/pubmed/36940705
http://dx.doi.org/10.1093/jrr/rrad007

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