Progressive Sub-MIC Exposure of Klebsiella pneumoniae 43816 to Cephalothin Induces the Evolution of Beta-Lactam Resistance without Acquisition of Beta-Lactamase Genes

Bacterial exposure to antibiotic concentrations below the minimum inhibitory concentration (MIC) may result in a selection window allowing for the rapid evolution of resistance. These sub-MIC concentrations are commonly found in soils and water supplies in the greater environment. This study aimed t...

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Detalles Bibliográficos
Autores principales: Anderson, Jasmine R., Lam, Nghi B., Jackson, Jazmyne L., Dorenkott, Sean M., Ticer, Taylor, Maldosevic, Emir, Velez, Amanda, Camden, Megan R., Ellis, Terri N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215138/
https://www.ncbi.nlm.nih.gov/pubmed/37237790
http://dx.doi.org/10.3390/antibiotics12050887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215138/
https://www.ncbi.nlm.nih.gov/pubmed/37237790
http://dx.doi.org/10.3390/antibiotics12050887

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