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Activation of NRF2 Signaling Pathway Delays the Progression of Hyperuricemic Nephropathy by Reducing Oxidative Stress

Hyperuricemia (HUA)-induced oxidative stress is a crucial contributor to hyperuricemic nephropathy (HN), but the molecular mechanisms underlying the disturbed redox homeostasis in kidneys remain elusive. Using RNA sequencing, together with biochemical analyses, we found that nuclear factor erythroid...

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Detalles Bibliográficos
Autores principales: Qiao, Panshuang, Sun, Yi, Wang, Yiming, Lin, Simei, An, Yongpan, Wang, Liang, Liu, Jihan, Huang, Yajun, Yang, Baoxue, Zhou, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215166/
https://www.ncbi.nlm.nih.gov/pubmed/37237889
http://dx.doi.org/10.3390/antiox12051022