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Synthesis and Biological Evaluation of O(6)-Aminoalkyl-Hispidol Analogs as Multifunctional Monoamine Oxidase-B Inhibitors towards Management of Neurodegenerative Diseases

Oxidative catabolism of monoamine neurotransmitters by monoamine oxidases (MAOs) produces reactive oxygen species (ROS), which contributes to neuronal cells’ death and also lowers monoamine neurotransmitter levels. In addition, acetylcholinesterase activity and neuroinflammation are involved in neur...

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Detalles Bibliográficos
Autores principales: Hassan, Ahmed H. E., Kim, Hyeon Jeong, Park, Keontae, Choi, Yeonwoo, Moon, Suyeon, Lee, Chae Hyeon, Kim, Yeon Ju, Cho, Soo Bin, Gee, Min Sung, Lee, Danbi, Park, Jong-Hyun, Lee, Jong Kil, Ryu, Jong Hoon, Park, Ki Duk, Lee, Yong Sup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215199/
https://www.ncbi.nlm.nih.gov/pubmed/37237899
http://dx.doi.org/10.3390/antiox12051033