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Synthesis and Biological Evaluation of O(6)-Aminoalkyl-Hispidol Analogs as Multifunctional Monoamine Oxidase-B Inhibitors towards Management of Neurodegenerative Diseases
Oxidative catabolism of monoamine neurotransmitters by monoamine oxidases (MAOs) produces reactive oxygen species (ROS), which contributes to neuronal cells’ death and also lowers monoamine neurotransmitter levels. In addition, acetylcholinesterase activity and neuroinflammation are involved in neur...
Autores principales: | Hassan, Ahmed H. E., Kim, Hyeon Jeong, Park, Keontae, Choi, Yeonwoo, Moon, Suyeon, Lee, Chae Hyeon, Kim, Yeon Ju, Cho, Soo Bin, Gee, Min Sung, Lee, Danbi, Park, Jong-Hyun, Lee, Jong Kil, Ryu, Jong Hoon, Park, Ki Duk, Lee, Yong Sup |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215199/ https://www.ncbi.nlm.nih.gov/pubmed/37237899 http://dx.doi.org/10.3390/antiox12051033 |
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