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Evidence of Copper Nanoparticles and Poly I:C Modulating Cas9 Interaction and Cleavage of COR (Conserved Omicron RNA)

Conserved omicron RNA (COR) is a 40 base long 99.9% conserved sequence in SARS-CoV-2 Omicron variant, predicted to form a stable stem loop, the targeted cleavage of which can be an ideal next step in controlling the spread of variants. The Cas9 enzyme has been traditionally utilized for gene editing...

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Detalles Bibliográficos
Autores principales: Karrer, Lindy G., Mathew, Elza Neelima, Nava-Chavez, Juliet, Bhatti, Abeera, Delong, Robert K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215437/
https://www.ncbi.nlm.nih.gov/pubmed/37237582
http://dx.doi.org/10.3390/bioengineering10050512