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Evidence of Copper Nanoparticles and Poly I:C Modulating Cas9 Interaction and Cleavage of COR (Conserved Omicron RNA)
Conserved omicron RNA (COR) is a 40 base long 99.9% conserved sequence in SARS-CoV-2 Omicron variant, predicted to form a stable stem loop, the targeted cleavage of which can be an ideal next step in controlling the spread of variants. The Cas9 enzyme has been traditionally utilized for gene editing...
Autores principales: | Karrer, Lindy G., Mathew, Elza Neelima, Nava-Chavez, Juliet, Bhatti, Abeera, Delong, Robert K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215437/ https://www.ncbi.nlm.nih.gov/pubmed/37237582 http://dx.doi.org/10.3390/bioengineering10050512 |
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