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Towards Novel Biomimetic In Vitro Models of the Blood–Brain Barrier for Drug Permeability Evaluation

Current available animal and in vitro cell-based models for studying brain-related pathologies and drug evaluation face several limitations since they are unable to reproduce the unique architecture and physiology of the human blood–brain barrier. Because of that, promising preclinical drug candidat...

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Detalles Bibliográficos
Autores principales: Mármol, Inés, Abizanda-Campo, Sara, Ayuso, Jose M., Ochoa, Ignacio, Oliván, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215475/
https://www.ncbi.nlm.nih.gov/pubmed/37237642
http://dx.doi.org/10.3390/bioengineering10050572