Sorangicin A Is Active against Chlamydia in Cell Culture, Explanted Fallopian Tubes, and Topical In Vivo Treatment

Current treatment of Chlamydia trachomatis using doxycycline and azithromycin introduces detrimental side effects on the host’s microbiota. As a potential alternative treatment, the myxobacterial natural product sorangicin A (SorA) blocks the bacterial RNA polymerase. In this study we analyzed the e...

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Detalles Bibliográficos
Autores principales: Graspeuntner, Simon, Koethke, Katharina, Scholz, Celeste, Semmler, Lea, Lupatsii, Mariia, Kirchhoff, Laura, Herrmann, Jennifer, Rox, Katharina, Wittstein, Kathrin, Käding, Nadja, Hanker, Lars C., Stadler, Marc, Brönstrup, Mark, Müller, Rolf, Shima, Kensuke, Rupp, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215493/
https://www.ncbi.nlm.nih.gov/pubmed/37237698
http://dx.doi.org/10.3390/antibiotics12050795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215493/
https://www.ncbi.nlm.nih.gov/pubmed/37237698
http://dx.doi.org/10.3390/antibiotics12050795

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