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Dietary Vitamin E and/or Hydroxytyrosol Supplementation to Sows during Late Pregnancy and Lactation Modifies the Lipid Composition of Colostrum and Milk

Modifying the composition of a sow’s milk could be a strategy to improve the intestinal health and growth of her piglet during the first weeks of life. This study evaluated how dietary supplementation of vitamin E (VE), hydroxytyrosol (HXT) or VE+HXT given to Iberian sows from late gestation affecte...

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Autores principales: Laviano, Hernan D., Gómez, Gerardo, Muñoz, María, García-Casco, Juan M., Nuñez, Yolanda, Escudero, Rosa, Molina, Ana Heras, González-Bulnes, Antonio, Óvilo, Cristina, López-Bote, Clemente, Rey, Ana I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215564/
https://www.ncbi.nlm.nih.gov/pubmed/37237905
http://dx.doi.org/10.3390/antiox12051039
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author Laviano, Hernan D.
Gómez, Gerardo
Muñoz, María
García-Casco, Juan M.
Nuñez, Yolanda
Escudero, Rosa
Molina, Ana Heras
González-Bulnes, Antonio
Óvilo, Cristina
López-Bote, Clemente
Rey, Ana I.
author_facet Laviano, Hernan D.
Gómez, Gerardo
Muñoz, María
García-Casco, Juan M.
Nuñez, Yolanda
Escudero, Rosa
Molina, Ana Heras
González-Bulnes, Antonio
Óvilo, Cristina
López-Bote, Clemente
Rey, Ana I.
author_sort Laviano, Hernan D.
collection PubMed
description Modifying the composition of a sow’s milk could be a strategy to improve the intestinal health and growth of her piglet during the first weeks of life. This study evaluated how dietary supplementation of vitamin E (VE), hydroxytyrosol (HXT) or VE+HXT given to Iberian sows from late gestation affected the colostrum and milk composition, lipid stability and their relationship with the piglet’s oxidative status. Colostrum from VE-supplemented sows had greater C18:1n−7 than non-supplemented sows, whereas HXT increased polyunsaturated (∑PUFAs), ∑n−6 and ∑n−3 fatty acids. In 7-day milk, the main effects were induced by VE supplementation that decreased ∑PUFAs, ∑n−6 and ∑n−3 and increased the Δ-6-desaturase activity. The VE+HXT supplementation resulted in lower desaturase capacity in 20-day milk. Positive correlations were observed between the estimated mean milk energy output and the desaturation capacity of sows. The lowest concentration of malondialdehyde (MDA) in milk was observed in VE-supplemented groups, whereas HXT supplementation increased oxidation. Milk lipid oxidation was negatively correlated with the sow’s plasma oxidative status and to a great extent with the oxidative status of piglets after weaning. Maternal VE supplementation produced a more beneficial milk composition to improve the oxidative status of piglets, which could promote gut health and piglet growth during the first weeks, but more research is needed to clarify this.
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spelling pubmed-102155642023-05-27 Dietary Vitamin E and/or Hydroxytyrosol Supplementation to Sows during Late Pregnancy and Lactation Modifies the Lipid Composition of Colostrum and Milk Laviano, Hernan D. Gómez, Gerardo Muñoz, María García-Casco, Juan M. Nuñez, Yolanda Escudero, Rosa Molina, Ana Heras González-Bulnes, Antonio Óvilo, Cristina López-Bote, Clemente Rey, Ana I. Antioxidants (Basel) Article Modifying the composition of a sow’s milk could be a strategy to improve the intestinal health and growth of her piglet during the first weeks of life. This study evaluated how dietary supplementation of vitamin E (VE), hydroxytyrosol (HXT) or VE+HXT given to Iberian sows from late gestation affected the colostrum and milk composition, lipid stability and their relationship with the piglet’s oxidative status. Colostrum from VE-supplemented sows had greater C18:1n−7 than non-supplemented sows, whereas HXT increased polyunsaturated (∑PUFAs), ∑n−6 and ∑n−3 fatty acids. In 7-day milk, the main effects were induced by VE supplementation that decreased ∑PUFAs, ∑n−6 and ∑n−3 and increased the Δ-6-desaturase activity. The VE+HXT supplementation resulted in lower desaturase capacity in 20-day milk. Positive correlations were observed between the estimated mean milk energy output and the desaturation capacity of sows. The lowest concentration of malondialdehyde (MDA) in milk was observed in VE-supplemented groups, whereas HXT supplementation increased oxidation. Milk lipid oxidation was negatively correlated with the sow’s plasma oxidative status and to a great extent with the oxidative status of piglets after weaning. Maternal VE supplementation produced a more beneficial milk composition to improve the oxidative status of piglets, which could promote gut health and piglet growth during the first weeks, but more research is needed to clarify this. MDPI 2023-05-03 /pmc/articles/PMC10215564/ /pubmed/37237905 http://dx.doi.org/10.3390/antiox12051039 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Laviano, Hernan D.
Gómez, Gerardo
Muñoz, María
García-Casco, Juan M.
Nuñez, Yolanda
Escudero, Rosa
Molina, Ana Heras
González-Bulnes, Antonio
Óvilo, Cristina
López-Bote, Clemente
Rey, Ana I.
Dietary Vitamin E and/or Hydroxytyrosol Supplementation to Sows during Late Pregnancy and Lactation Modifies the Lipid Composition of Colostrum and Milk
title Dietary Vitamin E and/or Hydroxytyrosol Supplementation to Sows during Late Pregnancy and Lactation Modifies the Lipid Composition of Colostrum and Milk
title_full Dietary Vitamin E and/or Hydroxytyrosol Supplementation to Sows during Late Pregnancy and Lactation Modifies the Lipid Composition of Colostrum and Milk
title_fullStr Dietary Vitamin E and/or Hydroxytyrosol Supplementation to Sows during Late Pregnancy and Lactation Modifies the Lipid Composition of Colostrum and Milk
title_full_unstemmed Dietary Vitamin E and/or Hydroxytyrosol Supplementation to Sows during Late Pregnancy and Lactation Modifies the Lipid Composition of Colostrum and Milk
title_short Dietary Vitamin E and/or Hydroxytyrosol Supplementation to Sows during Late Pregnancy and Lactation Modifies the Lipid Composition of Colostrum and Milk
title_sort dietary vitamin e and/or hydroxytyrosol supplementation to sows during late pregnancy and lactation modifies the lipid composition of colostrum and milk
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215564/
https://www.ncbi.nlm.nih.gov/pubmed/37237905
http://dx.doi.org/10.3390/antiox12051039
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