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Protective Effect and Mechanism of Xbp1s Regulating HBP/O-GlcNAcylation through GFAT1 on Brain Injury after SAH

(1) SAH induces cellular stress and endoplasmic reticulum stress, activating the unfolded protein response (UPR) in nerve cells. IRE1 (inositol-requiring enzyme 1) is a protein that plays a critical role in cellular stress response. Its final product, Xbp1s, is essential for adapting to changes in t...

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Detalles Bibliográficos
Autores principales: Wu, Kefan, Chen, Lili, Qiu, Zhen, Zhao, Bo, Hou, Jiabao, Lei, Shaoqin, Jiang, Meng, Xia, Zhongyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215646/
https://www.ncbi.nlm.nih.gov/pubmed/37238930
http://dx.doi.org/10.3390/biomedicines11051259