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Protective Effect and Mechanism of Xbp1s Regulating HBP/O-GlcNAcylation through GFAT1 on Brain Injury after SAH
(1) SAH induces cellular stress and endoplasmic reticulum stress, activating the unfolded protein response (UPR) in nerve cells. IRE1 (inositol-requiring enzyme 1) is a protein that plays a critical role in cellular stress response. Its final product, Xbp1s, is essential for adapting to changes in t...
Autores principales: | Wu, Kefan, Chen, Lili, Qiu, Zhen, Zhao, Bo, Hou, Jiabao, Lei, Shaoqin, Jiang, Meng, Xia, Zhongyuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215646/ https://www.ncbi.nlm.nih.gov/pubmed/37238930 http://dx.doi.org/10.3390/biomedicines11051259 |
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