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Lignan-Rich Sesame (Sesamum indicum L.) Cultivar Exhibits In Vitro Anti-Cholinesterase Activity, Anti-Neurotoxicity in Amyloid-β Induced SH-SY5Y Cells, and Produces an In Vivo Nootropic Effect in Scopolamine-Induced Memory Impaired Mice

Alzheimer’s disease, a major cause of dementia, is characterized by impaired cholinergic function, increased oxidative stress, and amyloid cascade induction. Sesame lignans have attracted considerable attention owing to their beneficial effects on brain health. This study investigated the neuroprote...

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Detalles Bibliográficos
Autores principales: Kim, Min-Young, Kim, Sungup, Lee, Jeongeun, Kim, Jung-In, Oh, Eunyoung, Kim, Sang-Woo, Lee, Eunsoo, Cho, Kwang-Soo, Kim, Choon-Song, Lee, Myoung-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215706/
https://www.ncbi.nlm.nih.gov/pubmed/37237976
http://dx.doi.org/10.3390/antiox12051110