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RETRO-TAS, a Retrospective Observational Study of Trifluridine/Tipiracil in Chemorefractory Metastatic Colorectal Cancer

Background: Trifluridine/tipiracil (FTD/TPI) is an oral antimetabolite agent comprised of trifluridine, a thymidine-based nucleoside analogue that inhibits cell proliferation following its incorporation into DNA, and tipiracil that helps maintain the blood concentration of trifluridine by inhibiting...

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Detalles Bibliográficos
Autores principales: Koumarianou, Anna, Ntavatzikos, Anastasios, Symeonidis, David, Vallilas, Christos, Giannakakou, Maria, Papaxoinis, Georgios, Xynogalos, Spyridon, Boukovinas, Ioannis, Demiri, Stamatina, Kampoli, Katerina, Oikonomopoulos, Georgios, Samantas, Epaminontas, Res, Eleni, Androulakis, Nikolaos, Vourli, Georgia, Souglakos, Ioannis, Karamouzis, Michalis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215810/
https://www.ncbi.nlm.nih.gov/pubmed/37238938
http://dx.doi.org/10.3390/biomedicines11051267