BET Protein Inhibitor JQ1 Modulates Mitochondrial Dysfunction and Oxidative Stress Induced by Chronic Kidney Disease

Among the mechanisms involved in the progression of kidney disease, mitochondrial dysfunction has special relevance. Epigenetic drugs such as inhibitors of extra-terminal domain proteins (iBET) have shown beneficial effects in experimental kidney disease, mainly by inhibiting proliferative and infla...

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Detalles Bibliográficos
Autores principales: Rayego-Mateos, Sandra, Basantes, Pamela, Morgado-Pascual, José Luis, Brazal Prieto, Beatriz, Suarez-Alvarez, Beatriz, Ortiz, Alberto, Lopez-Larrea, Carlos, Ruiz-Ortega, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215880/
https://www.ncbi.nlm.nih.gov/pubmed/37237996
http://dx.doi.org/10.3390/antiox12051130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215880/
https://www.ncbi.nlm.nih.gov/pubmed/37237996
http://dx.doi.org/10.3390/antiox12051130

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