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Contribution of Elevated Glucose and Oxidized LDL to Macrophage Inflammation: A Role for PRAS40/Akt-Dependent Shedding of Soluble CD14

Atherosclerosis, a process in which macrophages play a key role, is accelerated in diabetes. Elevated concentrations of serum-oxidized low-density lipoproteins (oxLDL) represent a common feature of both conditions. The main goal of this study was to determine the contribution of oxLDL to the inflamm...

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Detalles Bibliográficos
Autores principales: Sanjurjo, Lucía, Castelblanco, Esmeralda, Julve, Josep, Villalmanzo, Nuria, Téllez, Érica, Ramirez-Morros, Anna, Alonso, Núria, Mauricio, Dídac, Sarrias, Maria-Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215892/
https://www.ncbi.nlm.nih.gov/pubmed/37237950
http://dx.doi.org/10.3390/antiox12051083