Two-Pore-Domain Potassium Channel TREK–1 Mediates Pulmonary Fibrosis through Macrophage M2 Polarization and by Direct Promotion of Fibroblast Differentiation

Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by myofibroblast proliferation and abnormal accumulation of extracellular matrix in the lungs. After lung injury, M2 macrophages mediate the pathogenesis of pulmonary fibrosis by secreting fibrotic cytokines that promote myof...

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Detalles Bibliográficos
Autores principales: Zhang, Yunna, Fu, Jiafeng, Han, Yang, Feng, Dandan, Yue, Shaojie, Zhou, Yan, Luo, Ziqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215911/
https://www.ncbi.nlm.nih.gov/pubmed/37238950
http://dx.doi.org/10.3390/biomedicines11051279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215911/
https://www.ncbi.nlm.nih.gov/pubmed/37238950
http://dx.doi.org/10.3390/biomedicines11051279

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