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Acinetobacter baumannii under Acidic Conditions Induces Colistin Resistance through PmrAB Activation and Lipid A Modification

Colistin is a last-resort antimicrobial agent for treating carbapenem-resistant Acinetobacter baumannii infections. The activation of PmrAB by several environmental signals induces colistin resistance in Gram-negative bacteria. This study investigated the molecular mechanisms of colistin resistance...

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Detalles Bibliográficos
Autores principales: Ko, Seo-Yeon, Kim, Nayeong, Park, Seong-Yong, Kim, Seong-Yeop, Shin, Minsang, Lee, Je-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215926/
https://www.ncbi.nlm.nih.gov/pubmed/37237716
http://dx.doi.org/10.3390/antibiotics12050813