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A Combination of an Angiotensin II Receptor and a Neprilysin Inhibitor Attenuates Liver Fibrosis by Preventing Hepatic Stellate Cell Activation

The renin–angiotensin–aldosterone system has gained attention due to its role as a mediator of liver fibrosis and hepatic stellate cell (HSC) activation. Meanwhile, the natriuretic peptide (NP) system, including atrial NP (ANP) and C-type NP (CNP), is a counter-regulatory hormone regulated by nepril...

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Detalles Bibliográficos
Autores principales: Suzuki, Junya, Kaji, Kosuke, Nishimura, Norihisa, Kubo, Takahiro, Tomooka, Fumimasa, Shibamoto, Akihiko, Iwai, Satoshi, Tsuji, Yuki, Fujinaga, Yukihisa, Kitagawa, Koh, Namisaki, Tadashi, Akahane, Takemi, Yoshiji, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215948/
https://www.ncbi.nlm.nih.gov/pubmed/37238965
http://dx.doi.org/10.3390/biomedicines11051295