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Effects of Deacetylase Inhibition on the Activation of the Antioxidant Response and Aerobic Metabolism in Cellular Models of Fanconi Anemia

Fanconi anemia (FA) is a rare genetic disease characterized by a dysfunctional DNA repair and an oxidative stress accumulation due to defective mitochondrial energy metabolism, not counteracted by endogenous antioxidant defenses, which appear down-expressed compared to the control. Since the antioxi...

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Detalles Bibliográficos
Autores principales: Bertola, Nadia, Regis, Stefano, Bruno, Silvia, Mazzarello, Andrea Nicola, Serra, Martina, Lupia, Michela, Sabatini, Federica, Corsolini, Fabio, Ravera, Silvia, Cappelli, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215951/
https://www.ncbi.nlm.nih.gov/pubmed/37237966
http://dx.doi.org/10.3390/antiox12051100