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Effects of Deacetylase Inhibition on the Activation of the Antioxidant Response and Aerobic Metabolism in Cellular Models of Fanconi Anemia
Fanconi anemia (FA) is a rare genetic disease characterized by a dysfunctional DNA repair and an oxidative stress accumulation due to defective mitochondrial energy metabolism, not counteracted by endogenous antioxidant defenses, which appear down-expressed compared to the control. Since the antioxi...
Autores principales: | Bertola, Nadia, Regis, Stefano, Bruno, Silvia, Mazzarello, Andrea Nicola, Serra, Martina, Lupia, Michela, Sabatini, Federica, Corsolini, Fabio, Ravera, Silvia, Cappelli, Enrico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215951/ https://www.ncbi.nlm.nih.gov/pubmed/37237966 http://dx.doi.org/10.3390/antiox12051100 |
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